Chromosome 22 disorders

Nature

Chromosome 22 is the third smallest of the 46 pairs of chromosomes in humans. It is considered to be very gene rich, with an estimated 2,000 genes. 15% of it's sequence has already been determined, and approximately 150 genes have been identified already. There are many different disorders involving chromosome 22, such as trisomy 22 (many variations such as trisomy 22 mosaic, partial trisomy 22, translocation of 11 & 22 or other orphan translocations involving chromosome 22 and another chromosome) Cat Eye Syndrome, VeloCardioFacial Syndrome, DiGeorge Syndrome, Ring 22 and other deletions and translocations. It has also been implicated in bi-polar disorder and schizophrenia.

Claim

Chromosome 22 disorders represent a critical and often overlooked area of genetic research that demands urgent attention. These disorders, including DiGeorge syndrome and other microdeletion syndromes, profoundly impact individuals and families, leading to severe health challenges and developmental issues. The lack of awareness and funding for research hinders progress in diagnosis, treatment, and support. Addressing these disorders is not just a scientific obligation; it is a moral imperative to improve lives and foster understanding in genetics.

Counter-claim

While chromosome 22 disorders may seem concerning, they represent a minuscule fraction of genetic issues affecting the population. The focus on these rare conditions diverts attention and resources from more prevalent health crises that impact millions. Instead of fixating on the complexities of chromosome 22, we should prioritize widespread diseases and conditions that affect the majority, ensuring that our efforts yield the greatest benefit for public health. Let's not exaggerate the significance of this niche topic.